Increased levels of oxidants and reduced antioxidants in semen of infertile men with varicocele.
نویسندگان
چکیده
Significantly higher levels of oxidants (malonaldehyde and nitric oxide) and reduced levels of antioxidants (superoxide dismutase, glutathione peroxidase, catalase, and ascorbic acid) are seen in semen of infertile men with varicocele. Seminal oxidative stress (OS) seen in men with varicocele is associated with sperm motility and grade of varicocele.
منابع مشابه
P-114: Evaluation of GSTM1 Null Allele in Infertile Men with Varicocele
Background Varicocele is the abnormal inflexion and distension of veins of the pampiniform plexus within spermatic cord and is the most common and correctable known risk factor for male infertility. Varicoceles are found in approximately 40% of infertile men, whereas the incidence in the general male population is approximately 15%. Some studies suggest that varicocele is associated with elevat...
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Objective The main purpose of this study is to evaluate the effects of varicocelectomy on serum testosterone levels and semen quality in infertile men who suffer from varicocele. MaterialsAndMethods This prospective study enrolled 115 subjects with clinical varicocele grades II and III and 240 fertile men as the control group. Total volume of testosterone serum level (ng/dl) and semen quality w...
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Background: Post-acrosomal sheath WW domain binding protein (PAWP) is one of sperm factors related to oocyte activation and is expressed in elongating spermatid. Previously, the effect of high of testicular temperature in infertile men with varicocele on semen quality, sperm DNA damage, expression of genes and proteins were reported. In this study, expression of PAWP at RNA and protein levels, ...
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ورودعنوان ژورنال:
- Fertility and sterility
دوره 94 4 شماره
صفحات -
تاریخ انتشار 2010